Información ORCID de LECHUGA SANCHO, ALFONSO MARIA
Biografía
Información no disponible
Educación
MD, PhD.
Universidad de Cádiz Facultad de Medicina: Cádiz, ",
, España
Empleo
Universidad de Cádiz: Cádiz, Andalucía, España
Obras
Altered insulin secretion dynamics relate to oxidative stress and inflammasome activation in children with obesity and insulin resistance
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2023 | JOURNAL_ARTICLE
DOI: 10.1186/s12967-023-04337-7
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Metal Homeostasis and Exposure in Distinct Phenotypic Subtypes of Insulin Resistance among Children with Obesity
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2023 | JOURNAL_ARTICLE
DOI: 10.3390/nu15102347
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Altered Insulin Secretion Dynamics Relates to Oxidative Stress and Inflammasome Activation in Children with Obesity and Insulin Resistance
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2023 | OTHER
DOI: 10.21203/rs.3.rs-2777441/v1
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Impact of Parental Food Choices on Nutritional and Metabolic Status of Children with Type 1 Diabetes.
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2023 | JOURNAL_ARTICLE
DOI: 10.3390/foods12101969
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Assessment of the perception of vertical subjectivity in children born preterm
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2023 | JOURNAL_ARTICLE
DOI: 10.1007/s00431-023-04863-y
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Sexually dimorphic metal alterations in childhood obesity are modulated by a complex interplay between inflammation, insulin, and sex hormones.
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2023 | JOURNAL_ARTICLE
DOI: 10.1002/biof.1948
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Trace elements as potential modulators of puberty-induced amelioration of oxidative stress and inflammation in childhood obesity.
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2023 | JOURNAL_ARTICLE
DOI: 10.1002/biof.1946
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Analysis and Annotation of Phospholipids by Mass Spectrometry-Based Metabolomics.
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2023 | JOURNAL_ARTICLE
DOI: 10.1007/978-1-0716-2966-6_7
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Characterization of the Plasmatic and Erythroid Multielemental Biodistribution in Childhood Obesity Using a High-Throughput Method for Size Fractionation of Metal Species.
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2023 | JOURNAL_ARTICLE
DOI: 10.1007/978-1-0716-2699-3_12
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Exploring the association between circulating trace elements, metabolic risk factors, and the adherence to a Mediterranean diet among children and adolescents with obesity.
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2023 | JOURNAL_ARTICLE
DOI: 10.3389/fpubh.2022.1016819
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Untargeted Metabolomics Based on Liquid Chromatography-Mass Spectrometry for the Analysis of Plasma and Erythrocyte Samples in Childhood Obesity.
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2023 | JOURNAL_ARTICLE
DOI: 10.1007/978-1-0716-2699-3_11
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Altered Metal Homeostasis Associates with Inflammation, Oxidative Stress, Impaired Glucose Metabolism, and Dyslipidemia in the Crosstalk between Childhood Obesity and Insulin Resistance
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2022 | JOURNAL_ARTICLE
DOI: 10.3390/antiox11122439
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Assessment of the perception of vertical subjectivity in children born preterm
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2022 | OTHER
DOI: 10.21203/rs.3.rs-2382942/v1
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Proinflammatory Polyphosphate Increases in Plasma of Obese Children with Insulin Resistance and Adults with Severe Type 2 Diabetes.
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2022 | JOURNAL_ARTICLE
DOI: 10.3390/nu14214601
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Catalase post-translational modifications as key targets in the control of erythrocyte redox homeostasis in children with obesity and insulin resistance.
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2022 | JOURNAL_ARTICLE
DOI: 10.1016/j.freeradbiomed.2022.08.017
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Test-retest of the Subjective Visual Vertical Test performed using a mobile application with the smartphone anchored to a turntable.
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2022 | JOURNAL_ARTICLE
DOI: 10.1007/s00405-022-07512-6
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Adherence to Mediterranean Diet Is Associated With Better Glycemic Control in Children With Type 1 Diabetes: A Cross-Sectional Study.
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2022 | JOURNAL_ARTICLE
DOI: 10.3389/fnut.2022.813989
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Growth hormone treatment does not to lead to insulin resistance nor excessive rise in IGF‐1 levels, while improving height in patients small for gestational age A long‐term observational study
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2022 | JOURNAL_ARTICLE
DOI: 10.1111/cen.14626
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Levels of lactic acid's concordance with pH in pediatric parapneumonic pleural effusion.
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2021 | JOURNAL_ARTICLE
DOI: 10.1016/j.clinbiochem.2021.06.006
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Efficacy of the subjective visual vertical test performed using a mobile application to detect vestibular pathology.
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2021 | JOURNAL_ARTICLE
DOI: 10.3233/ves-201526
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Hybrid Closed-Loop System Achieves Optimal Perioperative Glycemia in a Boy With Type 1 Diabetes: A Case Report.
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2021 | JOURNAL_ARTICLE
DOI: 10.3389/fped.2021.625390
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Mechanistic Insights into Alzheimer’s Disease Unveiled through the Investigation of Disturbances in Central Metabolites and Metabolic Pathways
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2021 | JOURNAL_ARTICLE
DOI: 10.3390/biomedicines9030298
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Toxicity Induced by Cytokines, Glucose, and Lipids Increase Apoptosis and Hamper Insulin Secretion in the 1.1E7 Beta Cell-Line
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2021 | JOURNAL_ARTICLE
DOI: 10.3390/ijms22052559
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Blunted Reducing Power Generation in Erythrocytes Contributes to Oxidative Stress in Prepubertal Obese Children with Insulin Resistance
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2021 | JOURNAL_ARTICLE
DOI: 10.3390/antiox10020244
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Lung ultrasound score and diuretics in preterm infants born before 32 weeks: A pilot study.
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2020 | JOURNAL_ARTICLE
DOI: 10.1002/ppul.25098
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Placental Adaptive Changes to Protect Function and Decrease Oxidative Damage in Metabolically Healthy Maternal Obesity
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2020 | JOURNAL_ARTICLE
DOI: 10.3390/antiox9090794
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Iron Metabolism in Obesity and Metabolic Syndrome
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2020 | JOURNAL_ARTICLE
DOI: 10.3390/ijms21155529
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Plant catalases as NO and H2S targets
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2020 | JOURNAL_ARTICLE
DOI: 10.1016/j.redox.2020.101525
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Pleural line thickness reference values for preterm and term newborns.
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2020 | JOURNAL_ARTICLE
DOI: 10.1002/ppul.24920
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NT-proBNP plasma levels as biomarkers for pulmonary hypertension in healthy infants with respiratory syncytial virus infection.
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2019 | JOURNAL_ARTICLE
DOI: 10.2217/bmm-2018-0348
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SUN-255 PATRO Children, a Multi-Center, Non-Interventional Study of the Long-Term Safety and Efficacy of Omnitrope® in Children Requiring Growth Hormone Treatment: Comparing United States (US) and Rest of World (ROW) Data
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2019 | JOURNAL_ARTICLE
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GLP-1 mediated improvement of the glucose tolerance in the T2DM GK rat model after massive jejunal resection.
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2019 | JOURNAL_ARTICLE
DOI: 10.1016/j.aanat.2019.01.007
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Broad spectrum antibiotics in newborns increase multi-drug resistant infections.
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2019 | JOURNAL_ARTICLE
DOI: 10.1080/1120009x.2018.1556832
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High-Throughput Metabolomics Based on Direct Mass Spectrometry Analysis in Biomedical Research.
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2019 | JOURNAL_ARTICLE
DOI: 10.1007/978-1-4939-9236-2_3
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Topical Pharyngeal Lidocaine Reduces Respiratory Adverse Events During Upper Gastrointestinal Endoscopies Under Ketamine Sedation in Children.
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2018 | JOURNAL_ARTICLE
DOI: 10.1007/s40272-018-0320-2
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Excess Hydrocortisone Hampers Placental Nutrient Uptake Disrupting Cellular Metabolism.
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2018 | JOURNAL_ARTICLE
DOI: 10.1155/2018/5106174
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Intervention and Observational Trials Are Complementary in Metabolomics: Diabetes and the Oral Glucose Tolerance Test.
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2018 | JOURNAL_ARTICLE
DOI: 10.2174/1568026618666180711150525
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Normal Cerebellar Growth by Using Three-dimensional US in the Preterm Infant from Birth to Term-corrected Age.
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2018 | JOURNAL_ARTICLE
DOI: 10.1148/radiol.2018171956
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Heterozygous aggrecan variants are associated with short stature and brachydactyly: Description of 16 probands and a review of the literature.
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2018 | JOURNAL_ARTICLE
DOI: 10.1111/cen.13581
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Altered plasma-type gelsolin and amyloid-β in neonates with hypoxic-ischaemic encephalopathy under therapeutic hypothermia.
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2018 | JOURNAL_ARTICLE
DOI: 10.1177/0271678x18757419
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Decreased Retinal Thickness in Type 1 Diabetic Children with Signs of Nonproliferative Diabetic Retinopathy.
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2018 | JOURNAL_ARTICLE
DOI: 10.1155/2018/1078531
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Obesity induced alterations in redox homeostasis and oxidative stress are present from an early age.
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2018 | JOURNAL_ARTICLE
DOI: 10.1371/journal.pone.0191547
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Amplitude-Integrated EEG and Brain Sparing in Preterm Small-for-Gestational-Age Infants.
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2017 | JOURNAL_ARTICLE
DOI: 10.1097/wnp.0000000000000399
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[Spanish collaborative study: Description of usual clinical practice in infant obesity].
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2017 | JOURNAL_ARTICLE
DOI: 10.1016/j.anpedi.2017.07.008
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Bariatric surgery influences β-cell turnover in non obese rats.
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2017 | JOURNAL_ARTICLE
DOI: 10.14670/hh-11-909
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Supraventricular tachycardia after withdrawal of prolonged dexmedetomidine infusion in a paediatric patient without heart disease.
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2017 | JOURNAL_ARTICLE
DOI: 10.1111/jcpt.12564
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Synergic effects of sugar and caffeine on insulin-mediated metabolomic alterations after an acute consumption of soft drinks.
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2017 | JOURNAL_ARTICLE
DOI: 10.1002/elps.201700044
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Respiratory adverse events during upper digestive endoscopies in children under Ketamine sedation.
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2017 | JOURNAL_ARTICLE
DOI: 10.23736/s0026-4946.16.04758-7
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Thyroid hormone intoxication as a not yet described cause of J-wave syndrome in a pediatric patient.
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2017 | JOURNAL_ARTICLE
DOI: 10.1007/s12020-017-1228-2
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An Overview on the Importance of Combining Complementary Analytical Platforms in Metabolomic Research.
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2017 | JOURNAL_ARTICLE
DOI: 10.2174/1568026618666171211144918
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Ultrasound lineal measurements predict ventricular volume in post-haemorrhagic ventricular dilatation in preterm infants.
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2016 | JOURNAL_ARTICLE
DOI: 10.1111/apa.13645
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Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer's Disease.
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2016 | JOURNAL_ARTICLE
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Severe pneumonia by Mycoplasma as an adverse event of everolimus therapy in patients with tuberous sclerosis complex.
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2016 | JOURNAL_ARTICLE
DOI: 10.1016/j.ejpn.2016.05.002
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Ghrelin mitigates β-cell mass loss during insulitis in an animal model of autoimmune diabetes mellitus, the BioBreeding/Worcester rat.
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2017 | JOURNAL_ARTICLE
DOI: 10.1002/dmrr.2813
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Differences in the estrous cycles of Goto-Kakizaki and Wistar rats.
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2016 | JOURNAL_ARTICLE
DOI: 10.1038/laban.980
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Chest Pain in Children With Suspected Type I Fibrillinopathy: A Case Report.
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2015 | JOURNAL_ARTICLE
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Central vascular disease and exacerbated pathology in a mixed model of type 2 diabetes and Alzheimer's disease.
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2015 | JOURNAL_ARTICLE
DOI: 10.1016/j.psyneuen.2015.07.606
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Increased Spontaneous Central Bleeding and Cognition Impairment in APP/PS1 Mice with Poorly Controlled Diabetes Mellitus.
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2015 | JOURNAL_ARTICLE
DOI: 10.1007/s12035-015-9311-2
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[Recommendations of the Spanish Paediatric Endocrinology Society Working Group on Obesity on eating habits for the prevention of obesity and cardiovascular risk factors in childhood].
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2015 | JOURNAL_ARTICLE
DOI: 10.1016/j.anpedi.2015.06.004
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Desensitization to mecasermin in an insulin-like growth factor 1-deficient patient.
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2015 | JOURNAL_ARTICLE
DOI: 10.1016/j.anai.2015.03.004
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Epinephrine Improves the Efficacy of Nebulized Hypertonic Saline in Moderate Bronchiolitis: A Randomised Clinical Trial.
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2015 | JOURNAL_ARTICLE
DOI: 10.1371/journal.pone.0142847
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Ghrelin's Effects on Proinflammatory Cytokine Mediated Apoptosis and Their Impact on β-Cell Functionality.
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2015 | JOURNAL_ARTICLE
DOI: 10.1155/2015/235727
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A surgical model of short bowel syndrome induces a long-lasting increase in pancreatic beta-cell mass.
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2014 | JOURNAL_ARTICLE
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Prediabetes-induced vascular alterations exacerbate central pathology in APPswe/PS1dE9 mice.
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2014 | JOURNAL_ARTICLE
DOI: 10.1016/j.psyneuen.2014.06.005
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Does nebulized epinephrine improve the efficacy of hypertonic saline solution in the treatment of hospitalized moderate acute bronchiolitis? a double blind, randomized clinical trial.
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2014 | JOURNAL_ARTICLE
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Pneumonia and Purulent Pericarditis Caused by Streptococcus pneumoniae: An Uncommon Association in the Antibiotic Era.
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2014 | JOURNAL_ARTICLE
DOI: 10.1097/PEC.0000000000000186
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Toxicity of remedies for infantile colic.
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2014 | JOURNAL_ARTICLE
DOI: 10.1136/archdischild-2014-306885
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Low-voltage pattern and absence of sleep-wake cycles are associated with severe hemorrhage and death in very preterm infants.
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2014 | JOURNAL_ARTICLE
DOI: 10.1007/s00431-014-2360-0
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Central proliferation and neurogenesis is impaired in type 2 diabetes and prediabetes animal models.
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2014 | JOURNAL_ARTICLE
DOI: 10.1371/journal.pone.0089229
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[Obesity associated metabolic impairment is evident at early ages: spanish collaborative study].
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2014 | JOURNAL_ARTICLE
DOI: 10.3305/nh.2014.30.4.7661
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Differential central pathology and cognitive impairment in pre-diabetic and diabetic mice.
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2013 | JOURNAL_ARTICLE
DOI: 10.1016/j.psyneuen.2013.05.010
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Neuropsychological dysfunction and developmental defects associated with genetic changes in infants with neonatal diabetes mellitus: a prospective cohort study [corrected].
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2013 | JOURNAL_ARTICLE
DOI: 10.1016/S2213-8587(13)70059-7
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Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia.
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2013 | JOURNAL_ARTICLE
DOI: 10.1194/jlr.M031195
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Hepatocyte growth factor as an indicator of neonatal maturity.
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2013 | JOURNAL_ARTICLE
DOI: 10.1515/jpem-2012-0303
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Implications of family socioeconomic level on risk behaviors in child-youth obesity.
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2013 | JOURNAL_ARTICLE
DOI: 10.3305/nutr hosp.v28in06.6848
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Nitric oxide is a mediator of antiproliferative effects induced by proinflammatory cytokines on pancreatic beta cells.
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2013 | JOURNAL_ARTICLE
DOI: 10.1155/2013/905175
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Increased Aβ production prompts the onset of glucose intolerance and insulin resistance.
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2012 | JOURNAL_ARTICLE
DOI: 10.1152/ajpendo.00500.2011
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Novel mutation in the epithelial sodium channel causing type I pseudohypoaldosteronism in a patient misdiagnosed with cystic fibrosis.
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2012 | JOURNAL_ARTICLE
DOI: 10.1007/s00431-012-1697-5
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Safety of magnetic resonance imaging in preterm infants.
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2010 | JOURNAL_ARTICLE
DOI: 10.1111/j.1651-2227.2010.01708.x
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Predicting the growth response of children with idiopathic growth hormone deficiency to one year of recombinant growth hormone treatment: derivation and validation of a useful method.
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2009 | JOURNAL_ARTICLE
DOI: 10.1515/JPEM.2009.22.6.501
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Death of hypothalamic astrocytes in poorly controlled diabetic rats is associated with nuclear translocation of apoptosis inducing factor.
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2008 | JOURNAL_ARTICLE
DOI: 10.1111/j.1365-2826.2008.01795.x
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Cell-specific expression of X-linked inhibitor of apoptosis in the anterior pituitary of streptozotocin-induced diabetic rats.
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2007 | JOURNAL_ARTICLE
DOI: 10.1677/joe.1.06985
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Reduction in the number of astrocytes and their projections is associated with increased synaptic protein density in the hypothalamus of poorly controlled diabetic rats.
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2006 | JOURNAL_ARTICLE
DOI: 10.1210/en.2006-0766
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Increased apoptosis of lactotrophs in streptozotocin-induced diabetic rats is followed by increased proliferation.
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2006 | JOURNAL_ARTICLE
DOI: 10.1677/joe.1.06908
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Activation of the intrinsic cell death pathway, increased apoptosis and modulation of astrocytes in the cerebellum of diabetic rats.
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2006 | JOURNAL_ARTICLE
DOI: 10.1016/j.nbd.2006.03.001
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[Newborn with bladder extrophy associated with finasteride exposure]
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2004 | JOURNAL_ARTICLE
DOI: 10.1016/S1695-4033(04)78429-5
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Response of circulating ghrelin levels to insulin therapy in children with newly diagnosed type 1 diabetes mellitus.
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2004 | JOURNAL_ARTICLE
DOI: 10.1203/01.PDR.0000120679.92416.70
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Serum leptin concentrations during short-term administration of growth hormone and triiodothyronine in healthy adults: a randomised, double-blind placebo-controlled study.
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1999 | JOURNAL_ARTICLE
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